|
KMID : 0363320100310030612
|
|
Journal of Korean Oriental Internal Medicine
2010 Volume.31 No. 3 p.612 ~ p.619
|
|
|
May Low Level Laser Therapy be the Candidate of First Choice for the Acute Stroke?
|
|
Yang Chang-Sop
Jang In-San
Sun Seung-Ho
|
|
|
Abstract
|
|
|
Background:Low level laser therapy may be an effective method to protect tissue damage in acute stroke. Recently, series of clinical studies on the basis of animal experiments report efficacy and safety of laser therapy at early stages of acute stroke. Laser promotes mitochondrial ATP synthesis to reduce cell death by ischemic infarction.
Objectives:To report possibility of non-invasive laser therapy for acute stroke by reviewing literature about its effectiveness, safety and mechanism.
Methods:We searched papers using PubMed and ’Web of Knowledge’ of Thomson ISI, using the keywords "Laser Therapy, Low-Level" and "Stroke". Limitations were last 10 years of publications and only in English. Search range includes RCTs, clinical reports, reviews and animal experiments. Papers not matched with inclusion criteria were excluded.
Results:A total 223 studies were found, 203 excluded during title and extract screening. After scanning 20 papers the final 2 serial RCTs were selected and analyzed. They reported that transcranial laser therapy led in neuroprotective effect for acute stroke patents. Clinical evaluation factors showed favorable trend and initial safety.
Conclusions:Non-invasive laser secured safety of clinical application. It may be a favorable choice for the acute stage of stroke.
|
|
|
KEYWORD
|
|
|
Low level laser therapy, Transcranial laser therapy, Acute stroke, Efficacy, safety
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|